James Dewey Watson (born April 6, 1928) is an American
molecular biologist, geneticist, and zoologist, best known as a co-discoverer
of the structure of DNA in 1953 with Francis Crick. Watson, Crick, and Maurice
Wilkins were awarded the 1962 Nobel Prize in Physiology or Medicine "for
their discoveries concerning the molecular structure of nucleic acids and its
significance for information transfer in living material". After studies
at the University of Chicago and Indiana University, he worked at the University
of Cambridge's Cavendish Laboratory in England, where he first met his future
collaborator and friend Francis Crick.
Fifty years ago, James D.
Watson, then just twenty four, helped launch the greatest ongoing scientific
quest of our time. Now, with unique authority and sweeping vision, he gives us
the first full account of the genetic revolution—from Mendel’s garden to the
double helix to the sequencing of the human genome and beyond.
Watson’s lively, panoramic narrative
begins with the fanciful speculations of the ancients as to why “like begets
like” before skipping ahead to 1866, when an Austrian monk named Gregor Mendel
first deduced the basic laws of inheritance. But genetics as we recognize it
today—with its capacity, both thrilling and sobering, to manipulate the very
essence of living things—came into being only with the rise of molecular
investigations culminating in the breakthrough discovery of the structure of
DNA, for which Watson shared a Nobel prize in 1962. In the DNA molecule’s
graceful curves was the key to a whole new science.
Having shown that the secret of
life is chemical, modern genetics has set mankind off on a journey unimaginable
just a few decades ago. Watson provides the general reader with clear
explanations of molecular processes and emerging technologies. He shows us how
DNA continues to alter our understanding of human origins, and of our
identities as groups and as individuals. And with the insight of one who has
remained close to every advance in research since the double helix, he reveals
how genetics has unleashed a wealth of possibilities to alter the human
condition—from genetically modified foods to genetically modified babies—and
transformed itself from a domain of pure research into one of big business as
well. It is a sometimes topsy-turvy world full of great minds and great egos,
driven by ambitions to improve the human condition as well as to improve
investment portfolios, a world vividly captured in these pages.
Facing a future of choices and
social and ethical implications of which we dare not remain uninformed, we
could have no better guide than James Watson, who leads us with the same
bravura storytelling that made The Double Helix one of the most successful
books on science ever published. Infused with a scientist’s awe at nature’s
marvels and a humanist’s profound sympathies, DNA is destined to become the
classic telling of the defining scientific saga of our age.
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